Journal article
Impact of Insulin Receptor Substrate‐1 rs956115 and CYP2C19 rs4244285 Genotypes on Clinical Outcome of Patients Undergoing Percutaneous Coronary Intervention
Abstract
Background Insulin receptor substrate-1 (IRS-1) rs956115 is associated with vascular risk in patients with coronary artery disease and concomitant diabetes. CYP2C19*2 (rs4244285) modulates clopidogrel response and predicts the outcome of coronary artery disease. This study was designed to explore the association between IRS-1, CYP2C19*2 genotypes, platelet reactivity, and 1-year outcome in patients with coronary artery disease undergoing …
Authors
Zong J; Tang Y; Wang T; Ullah I; Xu K; Wang J; Chen P; Chen Z; Zhu T; Chen J
Journal
Journal of the American Heart Association, Vol. 11, No. 16,
Publisher
Wolters Kluwer
Publication Date
August 16, 2022
DOI
10.1161/jaha.121.025058
ISSN
2047-9980