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The past, present, and future of antibiotics
Journal article

The past, present, and future of antibiotics

Abstract

Antibiotics have transformed modern medicine. They are essential for treating infectious diseases and enable vital therapies and procedures. However, despite this success, their continued use in the 21st century is imperiled by two orthogonal challenges. The first is that the microbes targeted by these drugs evolve resistance to them over time. The second is that antibiotic discovery and development are no longer cost-effective using …

Authors

Cook MA; Wright GD

Journal

Science Translational Medicine, Vol. 14, No. 657,

Publisher

American Association for the Advancement of Science (AAAS)

Publication Date

August 10, 2022

DOI

10.1126/scitranslmed.abo7793

ISSN

1946-6234