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BDNF, proBDNF and IGF-1 serum levels in naïve and...
Journal article

BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

Abstract

Brain-derived neurotrophic factor (BDNF) and insulin-like growth factor 1 (IGF-1) promote the development and maintenance of neural circuits. Alterations in these factors might contribute to autism spectrum disorder (ASD). We asked whether serum BDNF, proBDNF, and IGF-1 levels are altered in an ASD population compared to controls. We measured serum BDNF, proBDNF, and IGF-1 immunoreactive protein in boys and girls aged 5–15 years old with mild …

Authors

Robinson-Agramonte MDLA; Michalski B; Vidal-Martinez B; Hernández LR; Santiesteban MW; Fahnestock M

Journal

Scientific Reports, Vol. 12, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41598-022-17503-6

ISSN

2045-2322