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Journal article

Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation

Abstract

Objective: Serum neurofilament light chain (sNfL) is increasingly used as a neuroaxonal injury biomarker in the elderly. Besides age, little is known about how other physiological factors like renal function and body mass index (BMI) alter its levels. Here, we investigated the association of estimated glomerular filtration rate (eGFR) and BMI with sNfL in a large sample of elderly patients with atrial fibrillation (AF). Methods: This is a …

Authors

Polymeris AA; Helfenstein F; Benkert P; Aeschbacher S; Leppert D; Coslovsky M; Willemse E; Schaedelin S; Blum MR; Rodondi N

Journal

Frontiers in Neuroscience, Vol. 16, ,

Publisher

Frontiers

DOI

10.3389/fnins.2022.819010

ISSN

1662-4548