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The effects of kindling on GABA-Mediated...
Journal article

The effects of kindling on GABA-Mediated inhibition in the dentate gyrus of the rat. I. Paired-pulse depression

Abstract

Double-pulse stimulation of the perforant path input to the dentate gyrus was used in the following experiments to produce paired pulse depression in that site. This effect provided an estimate of GABA-mediated recurrent inhibition. The depression was enhanced by drugs that facilitate or mimic GABA action and attenuated by drugs which block GABA transmission. Paired-pulse depression was significantly increased following amygdala kindling and …

Authors

Tuff LP; Racine RJ; Adamec R

Journal

Brain Research, Vol. 277, No. 1, pp. 79–90

Publisher

Elsevier

Publication Date

October 1983

DOI

10.1016/0006-8993(83)90909-5

ISSN

0006-8993