Journal article
Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts
Abstract
Papaya (Carica papaya) seeds were extracted in an aqueous buffer or in organic solvents, fractionated by chromatography on silica and aliquots tested for anthelmintic activity by viability assays using Caenorhabditis elegans. For all preparations and fractions tested, anthelmintic activity and benzyl isothiocyanate content correlated positively. Aqueous extracts prepared from heat-treated seeds had no anthelmintic activity or benzyl …
Authors
Kermanshai R; McCarry BE; Rosenfeld J; Summers PS; Weretilnyk EA; Sorger GJ
Journal
Phytochemistry, Vol. 57, No. 3, pp. 427–435
Publisher
Elsevier
Publication Date
June 2001
DOI
10.1016/s0031-9422(01)00077-2
ISSN
0031-9422