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Use of thrombolytic agents to treat neonatal...
Journal article

Use of thrombolytic agents to treat neonatal thrombosis in clinical practice

Abstract

Among children, neonates have the highest incidence of thrombosis. Thrombolytic agents are used for the management of life and/or organ-threatening thrombosis. Literature on the efficacy and safety of thrombolytic agents in neonates is limited. We reviewed the evidence on dosing, administration, monitoring and treatment duration of tissue plasminogen activator (tPA), streptokinase and urokinase (URK) in neonates (≤ 28days). A systematic …

Authors

Leong R; Patel J; Samji N; Paes BA; Chan AKC; Petropoulos J-A; Bhatt MD

Journal

Blood Coagulation & Fibrinolysis, Vol. 33, No. 4, pp. 193–200

Publisher

Wolters Kluwer

Publication Date

6 2022

DOI

10.1097/mbc.0000000000001134

ISSN

0957-5235