Journal article
CMET-35. PRELIMINARY SCREENING OF A NOVEL EpCAM BISPECIFIC T-CELL ENGAGER (BiTE) ANTIBODY TO TARGET A BMIC POPULATION IN HUMAN BRAIN METASTASES
Abstract
Brain Metastases (BM) are the most common type of cerebral tumor in adult, occurring at a rate 10 times greater than that of primary brain cancers. The inherent abilities of a primary tumor cell capable of initiating a BM resembles that of a cancer stem cell (CSC). Utilizing primary patient samples of BMs, we have characterized a subpopulation of CSC-like cells, termed brain metastasis-initiating cells (BMICs), which are responsible for …
Authors
Singh M; Venugopal C; Vora P; Adams J; Pan J; Chokshi C; Murty N; Sidhu S; Moffat J; Singh S
Journal
Neuro-Oncology, Vol. 19, No. suppl_6, pp. vi46–vi46
Publisher
Oxford University Press (OUP)
Publication Date
November 6, 2017
DOI
10.1093/neuonc/nox168.182
ISSN
1522-8517