Journal article
EXTH-53. ANTI-ROBO1 CAR T CELLS EFFECTIVELY TARGET MALIGNANT BRAIN CANCER
Abstract
Abstract
No standardized treatment exists for patients with recurrent glioblastoma (GBM). Given the aggressive nature of the disease and difficulty in modeling tumor recurrence, minimal efforts have been made to design rational therapies against it. The roundabout guidance receptor 1 (ROBO1) protein is involved in axonal guidance during neurodevelopment and is aberrantly upregulated in glioma where it mediates glioma cell …
Authors
Chokshi CR; Brakel B; Rossotti MA; Venugopal C; Salim S; Bloemberg D; Vora P; Henry KA; Singh SK
Journal
Neuro-Oncology, Vol. 23, No. Supplement_6, pp. vi175–vi175
Publisher
Oxford University Press (OUP)
Publication Date
November 12, 2021
DOI
10.1093/neuonc/noab196.692
ISSN
1522-8517