Journal article
Aqueous Humor Cytokine Levels and Anatomic Response to Intravitreal Ranibizumab in Diabetic Macular Edema
Abstract
Importance: Variability in response to anti-vascular endothelial growth factor (VEGF) treatment in diabetic macular edema (DME) remains a significant clinical challenge. Biomarkers could help anticipate responses to anti-VEGF therapy.
Objectives: To investigate aqueous humor cytokine level changes in response to intravitreal ranibizumab therapy for the management of DME, and to determine the association between baseline aqueous levels and …
Authors
Hillier RJ; Ojaimi E; Wong DT; Mak MYK; Berger AR; Kohly RP; Kertes PJ; Forooghian F; Boyd SR; Eng K
Journal
JAMA Ophthalmology, Vol. 136, No. 4, pp. 382–388
Publisher
American Medical Association (AMA)
Publication Date
April 1, 2018
DOI
10.1001/jamaophthalmol.2018.0179
ISSN
2168-6165
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultAgedAngiogenesis InhibitorsAqueous HumorBiomarkersCytokinesDiabetic RetinopathyDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesHumansIntravitreal InjectionsMacula LuteaMacular EdemaMaleMiddle AgedProspective StudiesRanibizumabTime FactorsTomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVisual Acuity