Journal article
The evolution of mean arterial pressure in critically ill patients on vasopressors before and during a trial comparing a specific mean arterial pressure target to usual care
Abstract
BackgroundIn randomized clinical controlled trials, the choice of usual care as the comparator may be associated with better clinician uptake of the study protocol and lead to more generalizable results. However, if care processes evolve to resemble the intervention during the course of a trial, differences between the intervention group and usual care control group may narrow. We evaluated the effect on mean arterial pressure of an unblinded …
Authors
Masse M-H; Adhikari NKJ; Théroux X; Battista M-C; D’Aragon F; Pinto R; Cohen A; Mayette M; St-Arnaud C; Kho M
Journal
BMC Anesthesiology, Vol. 22, No. 1,
Publisher
Springer Nature
Publication Date
December 2022
DOI
10.1186/s12871-021-01529-w
ISSN
1471-2253