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Effect of early treatment with fluvoxamine on risk...
Journal article

Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial

Abstract

BACKGROUND: Recent evidence indicates a potential therapeutic role of fluvoxamine for COVID-19. In the TOGETHER trial for acutely symptomatic patients with COVID-19, we aimed to assess the efficacy of fluvoxamine versus placebo in preventing hospitalisation defined as either retention in a COVID-19 emergency setting or transfer to a tertiary hospital due to COVID-19. METHODS: This placebo-controlled, randomised, adaptive platform trial done …

Authors

Reis G; dos Santos Moreira-Silva EA; Silva DCM; Thabane L; Milagres AC; Ferreira TS; dos Santos CVQ; de Souza Campos VH; Nogueira AMR; de Almeida APFG

Journal

The Lancet Global Health, Vol. 10, No. 1, pp. e42–e51

Publisher

Elsevier

Publication Date

January 2022

DOI

10.1016/s2214-109x(21)00448-4

ISSN

2572-116X