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Bidirectional brain–gut axis effects influence...
Journal article

Bidirectional brain–gut axis effects influence mood and prognosis in IBD: a systematic review and meta-analysis

Abstract

OBJECTIVE: The role of the brain-gut axis is of increasing interest in IBD, as the link between common mental disorders and GI inflammation may be bidirectional. We performed a systematic review examining these issues. DESIGN: We searched EMBASE Classic and EMBASE, Medline, and APA PsychInfo (to 11 July 2021) for longitudinal follow-up studies examining effect of symptoms of anxiety or depression on subsequent adverse outcomes in IBD, or effect …

Authors

Fairbrass KM; Lovatt J; Barberio B; Yuan Y; Gracie DJ; Ford AC

Journal

Gut, Vol. 71, No. 9, pp. 1773–1780

Publisher

BMJ

Publication Date

September 2022

DOI

10.1136/gutjnl-2021-325985

ISSN

0017-5749