Journal article
Eosinophil peroxidase in sputum represents a unique biomarker of airway eosinophilia
Abstract
BACKGROUND: Sputum eosinophilia has been shown to be a predictor of response to anti-eosinophil therapies in patients with airway diseases. However, quantitative cell counts and differentials of sputum are labor intensive. The objective of this study was to validate a novel ELISA-based assay of eosinophil peroxidase (EPX) in sputum as a rapid and reliable marker of airway eosinophils.
METHODS: The utility of EPX-based ELISA as an …
Authors
Nair P; Ochkur SI; Protheroe C; Radford K; Efthimiadis A; Lee NA; Lee JJ
Journal
Allergy, Vol. 68, No. 9, pp. 1177–1184
Publisher
Wiley
Publication Date
September 2013
DOI
10.1111/all.12206
ISSN
0001-5148