Journal article
A Microsimulation Model to Determine the Cost-Effectiveness of Treat-to-Target Strategies for Crohn's Disease
Abstract
INTRODUCTION: Cost-effectiveness of biomarker- vs endoscopy-based treat-to-target monitoring in Crohn's disease (CD) is unknown.
METHODS: A microsimulation model for CD was built to simulate biomarker (fecal calprotectin) vs endoscopy-based monitoring in a treat-to-target fashion. Published literature in combination with patient-level data from phase 3 clinical trials and population estimates for therapeutic drug monitoring were used to …
Authors
Dulai PS; Jairath V; Narula N; Wong E; Kochhar GS; Colombel J-F; Sandborn WJ
Journal
The American Journal of Gastroenterology, Vol. 116, No. 8, pp. 1709–1719
Publisher
Wolters Kluwer
Publication Date
August 2021
DOI
10.14309/ajg.0000000000001263
ISSN
0002-9270