Recalcitrant steroid-resistant EGPA with multisystem involvement

Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystem disorder classically characterized by sequential histopathologic and clinical disease phases. An eosinophilic tissue infiltration phase typically precedes the development of a systemic small-vessel vasculitic phase. The contribution of these two pathogenic mechanisms to disease course and the boundaries between them are often blurred. We report the case of a 49-year-old man …