Journal article
Prefrontal cortex VAMP1 gene network moderates the effect of the early environment on cognitive flexibility in children
Abstract
During development, genetic and environmental factors interact to modify specific phenotypes. Both in humans and in animal models, early adversities influence cognitive flexibility, an important brain function related to behavioral adaptation to variations in the environment. Abnormalities in cognitive functions are related to changes in synaptic connectivity in the prefrontal cortex (PFC), and altered levels of synaptic proteins. We …
Authors
Dalmaz C; Barth B; Pokhvisneva I; Wang Z; Patel S; Quillfeldt JA; Mendonça Filho EJ; de Lima RMS; Arcego DM; Sassi RB
Journal
Neurobiology of Learning and Memory, Vol. 185, ,
Publisher
Elsevier
Publication Date
11 2021
DOI
10.1016/j.nlm.2021.107509
ISSN
1074-7427