Journal article
Urine Alpha-1-Microglobulin Levels and Acute Kidney Injury, Mortality, and Cardiovascular Events following Cardiac Surgery
Abstract
INTRODUCTION: Urine alpha-1-microglobulin (Uα1m) elevations signal proximal tubule dysfunction. In ambulatory settings, higher Uα1m is associated with acute kidney injury (AKI), progressive chronic kidney disease (CKD), cardiovascular (CV) events, and mortality. We investigated the associations of pre- and postoperative Uα1m concentrations with adverse outcomes after cardiac surgery.
METHODS: In 1,464 adults undergoing cardiac surgery in the …
Authors
Amatruda JG; Estrella MM; Garg AX; Thiessen-Philbrook H; McArthur E; Coca SG; Parikh CR; Shlipak MG
Journal
American Journal of Nephrology, Vol. 52, No. 8, pp. 673–683
Publisher
Karger Publishers
Publication Date
2021
DOI
10.1159/000518240
ISSN
0250-8095