Heparin, Low Molecular Weight Heparin, and Heparin-Induced Thrombocytopenia in the ICU

Thrombocytopenia is common in critically ill patients who receive heparin. However, heparin-induced thrombocytopenia (HIT) is a relatively uncommon explanation for thrombocytopenia in this patient population. This article describes clinical features of HIT and interpretation of laboratory tests for HIT antibodies from the perspective of the intensive care unit.