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Antibiotic management of suspected nosocomial...
Journal article

Antibiotic management of suspected nosocomial ICU-acquired infection: Does prolonged empiric therapy improve outcome?

Abstract

ObjectiveTo characterize empiric antibiotic use in patients with suspected nosocomial ICU-acquired infections (NI), and determine the impact of prolonged therapy in the absence of infection.Design and settingMulticenter prospective cohort, with eight medical-surgical ICUs in North America and Europe.Patients195 patients with suspected NI.MethodsThe diagnosis of NI was adjudicated by a blinded Clinical Evaluation Committee using retrospective …

Authors

Aarts M-AW; Brun-Buisson C; Cook DJ; Kumar A; Opal S; Rocker G; Smith T; Vincent J-L; Marshall JC

Journal

Intensive Care Medicine, Vol. 33, No. 8, pp. 1369–1378

Publisher

Springer Nature

Publication Date

8 2007

DOI

10.1007/s00134-007-0723-y

ISSN

0342-4642