Journal article
Proton Pump Inhibitors Versus Histamine 2 Receptor Antagonists for Stress Ulcer Prophylaxis in Critically Ill Patients
Abstract
BACKGROUND: Critically ill patients may develop bleeding caused by stress ulceration. Acid suppression is commonly prescribed for patients at risk of stress ulcer bleeding. Whether proton pump inhibitors are more effective than histamine 2 receptor antagonists is unclear.
OBJECTIVES: To determine the efficacy and safety of proton pump inhibitors vs. histamine 2 receptor antagonists for the prevention of upper gastrointestinal bleeding in the …
Authors
Alhazzani W; Alenezi F; Jaeschke RZ; Moayyedi P; Cook DJ
Journal
Critical Care Medicine, Vol. 41, No. 3, pp. 693–705
Publisher
Wolters Kluwer
Publication Date
3 2013
DOI
10.1097/ccm.0b013e3182758734
ISSN
0090-3493