Journal article
Severity of Hypoxemia and Effect of High-Frequency Oscillatory Ventilation in Acute Respiratory Distress Syndrome
Abstract
RATIONALE: High-frequency oscillatory ventilation (HFOV) is theoretically beneficial for lung protection, but the results of clinical trials are inconsistent, with study-level meta-analyses suggesting no significant effect on mortality.
OBJECTIVES: The aim of this individual patient data meta-analysis was to identify acute respiratory distress syndrome (ARDS) patient subgroups with differential outcomes from HFOV.
Authors
Meade MO; Young D; Hanna S; Zhou Q; Bachman TE; Bollen C; Slutsky AS; Lamb SE; Adhikari NKJ; Mentzelopoulos SD
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 196, No. 6, pp. 727–733
Publisher
American Thoracic Society
Publication Date
September 15, 2017
DOI
10.1164/rccm.201609-1938oc
ISSN
1073-449X