Journal article
CTP:glycerol 3-phosphate cytidylyltransferase (TarD) from Staphylococcus aureus catalyzes the cytidylyl transfer via an ordered Bi–Bi reaction mechanism with micromolar Km values
Abstract
CTP:glycerol 3-phosphate cytidylyltransferase catalyzes the formation of CDP-glycerol, an activated form of glycerol 3-phosphate and key precursor to wall teichoic acid biogenesis in Gram-positive bacteria. There is high sequence identity (69%) between the CTP:glycerol 3-phosphate cytidylyltransferases from Bacillus subtilis 168 (TagD) and Staphylococcus aureus (TarD). The B. subtilis TagD protein was shown to catalyze cytidylyltransferase via …
Authors
Badurina DS; Zolli-Juran M; Brown ED
Journal
Biochimica et Biophysica Acta, Vol. 1646, No. 1-2, pp. 196–206
Publisher
Elsevier
Publication Date
3 2003
DOI
10.1016/s1570-9639(03)00019-0
ISSN
0006-3002