Journal article
Lack of evidence for a high-affinity sarcosinamide carrier or a catecholamine carrier in Calu-1 lung-cancer cells, HT-29 colon-cancer cells, and DHF fibroblasts
Abstract
We have previously demonstrated that uptake of the amino acid amide sarcosinamide by the glioma cell line SK-MG-1 occurs via the catecholamine carrier that accomodates epinephrine (Km=0.284mm; Vmax=0.154 nmol/106 cells/min). Sarcosinamide chloroethylnitrosourea (SarCNU), a new anticancer agent that exerts increased in vitro antitumor activity against gliomas as compared with BCNU (bis-chloroethylnitrosourea), the standard agent of choice, …
Authors
Malapetsa A; Bramson JL; Noë AJ; Panasci LC
Journal
Cancer Chemotherapy and Pharmacology, Vol. 31, No. 2, pp. 146–150
Publisher
Springer Nature
Publication Date
3 1992
DOI
10.1007/bf00685102
ISSN
0344-5704