Journal article
Relationship of Activated Partial Thromboplastin Time to Coronary Events and Bleeding in Patients With Acute Coronary Syndromes Who Receive Heparin
Abstract
BACKGROUND: Antithrombotic therapy with intravenous heparin in conjunction with aspirin reduces negative cardiovascular (CV) outcomes in patients with acute coronary syndromes. The need for a therapeutic range with the activated partial thromboplastin time (APTT) has not been validated in patients with arterial thrombosis who receive heparin. Therefore, it is unclear whether there is an association between recurrent CV events and low APTT …
Authors
Anand SS; Yusuf S; Pogue J; Ginsberg JS; Hirsh J
Journal
Circulation, Vol. 107, No. 23, pp. 2884–2888
Publisher
Wolters Kluwer
Publication Date
June 17, 2003
DOI
10.1161/01.cir.0000077530.53367.e9
ISSN
0009-7322
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Acute DiseaseAnticoagulantsAspirinCoronary DiseaseFemaleHemorrhageHeparinHumansMaleMiddle AgedMulticenter Studies as TopicPartial Thromboplastin TimePlatelet Aggregation InhibitorsPredictive Value of TestsRandomized Controlled Trials as TopicReproducibility of ResultsRiskSecondary PreventionTreatment Outcome