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Chemokine Receptor CXCR3 Expression in...
Journal article

Chemokine Receptor CXCR3 Expression in Inflammatory Bowel Disease

Abstract

CD4+ T lymphocytes in the lamina propria (LP) of the gut play a central role in the immune response in inflammatory bowel disease (IBD). CXCR3 is a chemokine receptor expressed on activated T lymphocytes, and a key component for the recruitment of T helper (Th1) effector cells to the site of inflammation. To determine if CXCR3 is involved in localization of T cells to the gut in IBD patients, we investigated the expression of CXCR3 on CD4+ T …

Authors

Yuan Y-H; Hove TT; Olle The F; Slors JFM; van Deventer SJH; Velde AAT

Journal

Inflammatory Bowel Diseases, Vol. 7, No. 4, pp. 281–286

Publisher

Oxford University Press (OUP)

Publication Date

November 2001

DOI

10.1097/00054725-200111000-00001

ISSN

1078-0998