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Pharmacodynamic effects of indobufen compared with...
Journal article

Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis

Abstract

PurposeThis study aimed to investigate the pharmacodynamic effects of indobufen and low-dose aspirin in patients with coronary atherosclerosis.MethodsIn the first phase, 218 patients with coronary atherosclerosis were randomly assigned to receive aspirin 100 mg once daily (standard dose); 100 mg once every 2 days; 100 mg once every 3 days; 50 mg twice daily; 75 mg once daily; 50 mg once daily; or indobufen 100 mg twice daily for 1 month. In the …

Authors

Yang M; Ye Z; Mei L; Ullah I; Tan C; Wang G; Gu Q; Lu Y; Abdus S; Shi L

Journal

European Journal of Clinical Pharmacology, Vol. 77, No. 12, pp. 1815–1823

Publisher

Springer Nature

Publication Date

12 2021

DOI

10.1007/s00228-021-03177-y

ISSN

0031-6970