Journal article
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes
Abstract
To identify type 2 diabetes (T2D) susceptibility loci, we conducted genome-wide association (GWA) scans in nested case-control samples from two prospective cohort studies, including 2591 patients and 3052 controls of European ancestry. Validation was performed in 11 independent GWA studies of 10,870 cases and 73,735 controls. We identified significantly associated variants near RBMS1 and ITGB6 genes at 2q24, best-represented by SNP rs7593730 …
Authors
Qi L; Cornelis MC; Kraft P; Stanya KJ; Kao WHL; Pankow JS; Dupuis J; Florez JC; Fox CS; Paré G
Journal
Human Molecular Genetics, Vol. 19, No. 13, pp. 2706–2715
Publisher
Oxford University Press (OUP)
Publication Date
July 1, 2010
DOI
10.1093/hmg/ddq156
ISSN
0964-6906