Journal article
DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome
Abstract
Genomic, chromosomal, and gene-specific changes in the DNA sequence underpin both phenotypic variations in populations as well as disease associations, and the application of genomic technologies for the identification of constitutional (inherited) or somatic (acquired) alterations in DNA sequence forms a cornerstone of clinical and molecular genetics. In addition to the disruption of primary DNA sequence, the modulation of DNA function by …
Authors
Schenkel LC; Rodenhiser DI; Ainsworth PJ; Paré G; Sadikovic B
Journal
Critical Reviews in Clinical Laboratory Sciences, Vol. 53, No. 3, pp. 147–165
Publisher
Taylor & Francis
Publication Date
May 3, 2016
DOI
10.3109/10408363.2015.1113496
ISSN
1040-8363