Journal article
Underestimation of airway luminal eosinophilia by quantitative sputum cytometry
Abstract
RationaleOn Wright-stained sputum cytospins, eosinophil differential of ≥ 1.2% is considered abnormal, and ≥ 2.3% identifies an eosinophilic endotype. We hypothesized that failure to consider free eosinophil granules (FEG), and the re-emergence (unmasking) of eosinophilia due to various reasons underestimate the prevalence of the eosinophilic endotype.MethodsThis is a retrospective analysis of our Institutional Review Board-approved clinical …
Authors
Kjarsgaard M; Adatia A; Bhalla A; LaVigne N; Radford K; Huang C; Mukherjee M; Nair P
Journal
Allergy, Asthma & Clinical Immunology, Vol. 17, No. 1,
Publisher
Springer Nature
Publication Date
12 2021
DOI
10.1186/s13223-021-00567-w
ISSN
1710-1484