Journal article
Characterization of human embryonic stem cells with features of neoplastic progression
Abstract
Werbowetski-Ogilvie et al. show that cultured human embryonic stem (hES) cells that appear normal may in fact be partially transformed. Two such lines are found to have aberrant growth and differentiation properties and submicroscopic chromosomal abnormalities.
Authors
Werbowetski-Ogilvie TE; Bossé M; Stewart M; Schnerch A; Ramos-Mejia V; Rouleau A; Wynder T; Smith M-J; Dingwall S; Carter T
Journal
Nature Biotechnology, Vol. 27, No. 1, pp. 91–97
Publisher
Springer Nature
Publication Date
January 2009
DOI
10.1038/nbt.1516
ISSN
1087-0156