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Novel roles for Notch, Wnt and Hedgehog in...
Journal article

Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells

Abstract

Human pluripotent stem cells (PSCs) derived from a number of different sources, including reprogrammed adult somatic cells, provide a powerful cellular system to study signaling pathways implicated in cell fate decisions, and generate new sources of cells for regenerative medicine. To realize this potential, it is essential to control the direction and efficiency of human PSC differentiation. Although Notch, Wnt and Hedgehog (HH) signaling …

Authors

Cerdan C; Bhatia M

Journal

The International Journal of Developmental Biology, Vol. 54, No. 6-7, pp. 955–964

Publisher

UPV/EHU Press

Publication Date

2010

DOI

10.1387/ijdb.103067cc

ISSN

0214-6282