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976P Efficacy of immune checkpoint inhibitors...
Conference

976P Efficacy of immune checkpoint inhibitors (ICI) and genomic alterations by body mass index (BMI) in advanced renal cell carcinoma (RCC)

Abstract

Background An elevated BMI is associated with improved prognosis in certain solid tumors treated with ICI; however, real-world data and genomic analysis has been lacking. We investigated the effect of BMI on RCC patients treated with PD-1/PD-L1 based ICI and explored potential genomic alterations (GA). Methods Using the International Metastatic RCC Database Consortium (IMDC) database, we performed a retrospective analysis on patients treated …

Authors

Lalani A-KA; Bakouny Z; Farah S; Xie W; Flippot R; Steinharter JA; Nuzzo PV; Fleischer J; Pal SK; Rathi N

Volume

30

Publisher

Elsevier

Publication Date

October 2019

DOI

10.1093/annonc/mdz249.072

Conference proceedings

Annals of Oncology

ISSN

0923-7534