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P01-293 Gender differences in brain serotonin...
Journal article

P01-293 Gender differences in brain serotonin synthesis in individuals with major depressive disorder: A A-[11C]MT pet imaging study

Abstract

Objective: Women are at higher risk than men to develop major depressive disorder (MDD), but the mechanisms underlying the higher risk for MDD in women are unknown. There is a wealth of data showing gender differences in brain morphology and function. In addition, preclinical studies have demonstrated reciprocal relationships between ovarian hormones and serotonin neurotransmission. Thus, gender differences in brain serotonin neurotransmission …

Authors

Frey BN; Skelin I; Sakai Y; Nishikawa M; Diksic M

Journal

European Psychiatry, Vol. 24, No. S1,

Publisher

Cambridge University Press (CUP)

Publication Date

January 2009

DOI

10.1016/s0924-9338(09)70914-9

ISSN

0924-9338