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Urinary EGF and MCP-1 and risk of CKD after...
Journal article

Urinary EGF and MCP-1 and risk of CKD after cardiac surgery

Abstract

BACKGROUNDAssessment of chronic kidney disease (CKD) risk after acute kidney injury (AKI) is based on limited markers primarily reflecting glomerular function. We evaluated markers of cell integrity (EGF) and inflammation (monocyte chemoattractant protein-1, MCP-1) for predicting long-term kidney outcomes after cardiac surgery.METHODSWe measured EGF and MCP-1 in postoperative urine samples from 865 adults who underwent cardiac surgery at 2 …

Authors

Menez S; Ju W; Menon R; Moledina DG; Philbrook HT; McArthur E; Jia Y; Obeid W; Mansour SG; Koyner JK

Journal

JCI Insight, Vol. 6, No. 11,

Publisher

American Society for Clinical Investigation

DOI

10.1172/jci.insight.147464

ISSN

2379-3708