Journal article
Independent and combined effects of biotin and hemolysis on high-sensitivity cardiac troponin assays
Abstract
OBJECTIVES: This study compared the independent and combined effects of hemolysis and biotin on cardiac troponin measurements across nine high-sensitivity cardiac troponin (hs-cTn) assays.
METHODS: Parallel cTn measurements were made in pooled lithium heparin plasma spiked with hemolysate and/or biotin using nine hs-cTn assays: Abbott Alinity, Abbott ARCHITECT i2000, Beckman Access 2, Ortho VITROS XT 7600, Siemens Atellica, Siemens Centaur, …
Authors
Harley K; Bissonnette S; Inzitari R; Schulz K; Apple FS; Kavsak PA; Gunsolus IL
Journal
Clinical Chemistry and Laboratory Medicine, Vol. 59, No. 8, pp. 1431–1443
Publisher
De Gruyter
Publication Date
July 1, 2021
DOI
10.1515/cclm-2021-0124
ISSN
1434-6621