Journal article
Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend for Macular Edema in Central Retinal Vein Occlusion: the CENTERA Study
Abstract
PURPOSE: To evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) treat-and-extend dosing in patients with macular edema secondary to central retinal vein occlusion (CRVO).
DESIGN: CENTERA (Evaluation of a Treat and Extend Regimen of Intravitreal Aflibercept for Macular Edema Secondary to CRVO; NCT02800642) was an open-label, Phase 4 clinical study.
Authors
Korobelnik J-F; Larsen M; Eter N; Bailey C; Wolf S; Schmelter T; Allmeier H; Chaudhary V
Journal
American Journal of Ophthalmology, Vol. 227, , pp. 106–115
Publisher
Elsevier
Publication Date
July 2021
DOI
10.1016/j.ajo.2021.01.027
ISSN
0002-9394
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdolescentAdultAgedAged, 80 and overAngiogenesis InhibitorsFemaleHumansIntravitreal InjectionsMacular EdemaMaleMiddle AgedReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinal Vein OcclusionTomography, Optical CoherenceTreatment OutcomeVascular Endothelial Growth Factor AVisual Acuity