Journal article
Interferon Gamma in Successful Pregnancies1
Abstract
Interferon gamma (IFNG) is a proinflammatory cytokine secreted in the uterus during early pregnancy. It is abundantly produced by uterine natural killer cells in maternal endometrium but also by trophoblasts in some species. In normal pregnancies of mice, IFNG plays critical roles that include initiation of endometrial vasculature remodeling, angiogenesis at implantation sites, and maintenance of the decidual (maternal) component of the …
Authors
Murphy SP; Tayade C; Ashkar AA; Hatta K; Zhang J; Croy BA
Journal
Biology of Reproduction, Vol. 80, No. 5, pp. 848–859
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2009
DOI
10.1095/biolreprod.108.073353
ISSN
0006-3363