Prolonged Improvement in Patient Reported Quality of Life (QoL) Following Tisagenlecleucel Infusion in Adult Patients (pts) with Relapsed/Refractory (r/r) Diffuse Large B-Cell Lymphoma (DLBCL): 19-Month Follow-up (FU) of the Juliet Study

Background Quality of life (QoL) is an important endpoint in the JULIET study (NCT02445248), a phase 2 trial evaluating a single infusion of tisagenlecleucel in adult patients (pts) with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL). Earlier analyses showed improvements in QoL at month (mo) 3 and 6 (Maziarz et al, ASH 2017, EBMT 2018). We report updated JULIET data with extended follow-up (FU; median: 19.3 mo). Methods Pts …