Journal article
NOD1 activation induces oxidative stress via NOX1/4 in adipocytes
Abstract
Activation of innate immune components promotes cell autonomous inflammation in adipocytes. Oxidative stress links pattern recognition receptor-mediated detection of inflammatory ligands and the immune response. Reactive oxygen species (ROS) may mediate the effect of nucleotide-binding oligomerization domain protein-1 (NOD1) activation on inflammation in adipocytes. Here, we define the potential role of NADPH oxidase (NOX)-derived ROS in …
Authors
Sharma A; Singh S; Ahmad S; Gulzar F; Schertzer JD; Tamrakar AK
Journal
Free Radical Biology and Medicine, Vol. 162, , pp. 118–128
Publisher
Elsevier
Publication Date
January 2021
DOI
10.1016/j.freeradbiomed.2020.11.036
ISSN
0891-5849