Single step separation and concentration of biomarker proteins using agarose based miniaturized isoelectric gates for point of care diagnostics

Bedside diagnostics using protein biomarkers requires rapid concentration, isolation and measurement of these specific biomarkers from a complex matrix in a low cost and portable manner. Traditional separation using gel electrophoresis separates the sample into all its constituent elements and requires high voltages and/or long runtime which is often unnecessary for diagnostics where only a specific biomarker needs to be quantified. Digital …