Journal article
Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials
Abstract
PurposeWith the publication of a large randomized-controlled trial (RCT) suggesting that tranexamic acid (TXA) may improve head-injury-related deaths, we aimed to determine the safety and efficacy of TXA in acute traumatic brain injury (TBI).MethodsIn this systematic review and meta-analysis, we searched MEDLINE, PubMed, EMBASE, CINHAL, ACPJC, Google Scholar, and unpublished sources from inception until June 24, 2020 for randomized-controlled …
Authors
Lawati KA; Sharif S; Maqbali SA; Rimawi HA; Petrosoniak A; Belley-Cote EP; Sharma SV; Morgenstern J; Fernando SM; Owen JJ
Journal
Intensive Care Medicine, Vol. 47, No. 1, pp. 14–27
Publisher
Springer Nature
Publication Date
1 2021
DOI
10.1007/s00134-020-06279-w
ISSN
0342-4642