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Journal article

Structural neuroimaging biomarkers for obsessive-compulsive disorder in the ENIGMA-OCD consortium: medication matters

Abstract

No diagnostic biomarkers are available for obsessive-compulsive disorder (OCD). Here, we aimed to identify magnetic resonance imaging (MRI) biomarkers for OCD, using 46 data sets with 2304 OCD patients and 2068 healthy controls from the ENIGMA consortium. We performed machine learning analysis of regional measures of cortical thickness, surface area and subcortical volume and tested classification performance using cross-validation. …

Authors

Bruin WB; Taylor L; Thomas RM; Shock JP; Zhutovsky P; Abe Y; Alonso P; Ameis SH; Anticevic A; Arnold PD

Journal

Translational Psychiatry, Vol. 10, No. 1,

Publisher

Springer Nature

DOI

10.1038/s41398-020-01013-y

ISSN

2158-3188