Journal article
Plasma ACE2 and risk of death or cardiometabolic diseases: a case-cohort analysis
Abstract
BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) is an endogenous counter-regulator of the renin-angiotensin hormonal cascade. We assessed whether plasma ACE2 concentrations were associated with greater risk of death or cardiovascular disease events.
METHODS: We used data from the Prospective Urban Rural Epidemiology (PURE) prospective study to conduct a case-cohort analysis within a subset of PURE participants (from 14 countries across five …
Authors
Narula S; Yusuf S; Chong M; Ramasundarahettige C; Rangarajan S; Bangdiwala SI; van Eikels M; Leineweber K; Wu A; Pigeyre M
Journal
The Lancet, Vol. 396, No. 10256, pp. 968–976
Publisher
Elsevier
Publication Date
October 2020
DOI
10.1016/s0140-6736(20)31964-4
ISSN
0140-6736