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Selection and management of older patients with...
Journal article

Selection and management of older patients with acute myeloid leukemia treated with glasdegib plus low-dose cytarabine: expert panel review

Abstract

Glasdegib, in combination with low-dose cytarabine (LDAC), is the first smoothened inhibitor approved for treatment of acute myeloid leukemia. Glasdegib plus LDAC is indicated for patients in whom therapy options are limited, e.g. older patients and those ineligible for intensive chemotherapy due to preexisting comorbidities. This review summarizes the recommendations of a panel of hemato-oncologists regarding the selection of patients best …

Authors

Cortes JE; Candoni A; Clark RE; Leber B; Montesinos P; Vyas P; Zeidan AM; Heuser M

Journal

Leukemia & Lymphoma, Vol. 61, No. 14, pp. 3287–3305

Publisher

Taylor & Francis

Publication Date

December 5, 2020

DOI

10.1080/10428194.2020.1817445

ISSN

1042-8194