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Week 6 Calprotectin Best Predicts Likelihood of...
Journal article

Week 6 Calprotectin Best Predicts Likelihood of Long-term Endoscopic Healing in Crohn’s Disease: A Post-hoc Analysis of the UNITI/IM-UNITI Trials

Abstract

OBJECTIVES: There is need for biomarkers as predictors of outcome of medical treatment in Crohn's disease. The purpose of this study was to evaluate the predictive performance of faecal calprotectin for short- and long-term clinical and endoscopic outcomes. METHODS: This post-hoc analysis of the UNITI/IM-UNITI studies [NCT01369329, NCT01369342, and NCT01369355; YODA #2019-4026] included 677 patients to evaluate the relationship of Week 6 …

Authors

Narula N; Wong ECL; Dulai PS; Marshall JK; Colombel J-F; Reinisch W

Journal

Journal of Crohn's and Colitis, Vol. 15, No. 3, pp. 462–470

Publisher

Oxford University Press (OUP)

Publication Date

March 5, 2021

DOI

10.1093/ecco-jcc/jjaa189

ISSN

1197-4982