Increased Risk of Death in Acutely Ill Medical Patients with Asymptomatic Proximal Deep Vein Thrombosis or Symptomatic Venous Thromboembolism: Insights from the Magellan Study

Background: Asymptomatic proximal deep-vein thrombosis (ASxDVT) is an efficacy endpoint that has been used for several decades in clinical trials evaluating thromboprophylaxis with anticoagulants. Previous studies have suggested the finding of ASxDVT on routine ultrasonography is associated with increased subsequent all-cause mortality (ACM). We evaluated the relationship between ASxDVT and subsequent ACM using the data from the MAGELLAN study …