Journal article
Genetically Determined Height and Coronary Artery Disease
Abstract
BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear.
METHODS: We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of CAD in 65,066 cases and 128,383 controls. …
Authors
Nelson CP; Hamby SE; Saleheen D; Hopewell JC; Zeng L; Assimes TL; Kanoni S; Willenborg C; Burgess S; Amouyel P
Journal
The New England Journal of Medicine, Vol. 372, No. 17, pp. 1608–1618
Publisher
Massachusetts Medical Society
Publication Date
April 23, 2015
DOI
10.1056/nejmoa1404881
ISSN
0028-4793