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Journal article

GWAS-identified genetic variants associated with medication-assisted treatment outcomes in patients with opioid use disorder: a systematic review and meta-analysis protocol

Abstract

BackgroundThe burden of opioid use disorder (OUD) has been increasing in North America. Administration of medication-assisted treatments (MATs) for OUD on an individual-dose basis has been shown to affect patient responses to treatment, proving to be, on occasion, dangerous. A genetic basis has been identified for some MAT responses in a candidate gene context, but consensus has not been reached for any genome-wide significant associations. …

Authors

Chawar C; Hillmer A; Sanger S; D’Elia A; Panesar B; Guan L; Xie DX; Bansal N; Abdullah A; Kapczinski F

Journal

Systematic Reviews, Vol. 9, No. 1,

Publisher

Springer Nature

Publication Date

12 2020

DOI

10.1186/s13643-020-01461-z

ISSN

2046-4053