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Stopping renin-angiotensin system blockers after...
Journal article

Stopping renin-angiotensin system blockers after acute kidney injury and risk of adverse outcomes: parallel population-based cohort studies in English and Swedish routine care

Abstract

BackgroundThe safety of restarting angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARB) after acute kidney injury (AKI) is unclear. There is concern that previous users do not restart ACEI/ARB despite ongoing indications. We sought to determine the risk of adverse events after an episode of AKI, comparing prior ACEI/ARB users who stop treatment to those who continue.MethodsWe conducted two parallel cohort …

Authors

Bidulka P; Fu EL; Leyrat C; Kalogirou F; McAllister KSL; Kingdon EJ; Mansfield KE; Iwagami M; Smeeth L; Clase CM

Journal

BMC Medicine, Vol. 18, No. 1,

Publisher

Springer Nature

Publication Date

December 2020

DOI

10.1186/s12916-020-01659-x

ISSN

1741-7015